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As the presented experiments do not report absolute changes in alcohol drinking after GLP-1R agonist treatment, the effectiveness of the different agonists cannot be compared

Cells were washed with cold PBS and lysed directly in the plate using the lysis buffer provided by the RNeasy kit (QIAGEN) at time points 1.5, 3, 6, 12, and 24 h

These and other risks are described more fully in PMGCs filings with the United States Securities and Exchange Commission (SEC), including the Risk Factors section of the Companys Annual Report on Form 10-K for the year ended December 31, 2025, filed with the SEC on March 30, 2026, and its other documents subsequently filed with or furnished to the SEC

Long-term depression in hippocampal interneurons: joint requirement for pre- and postsynaptic events